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   Skin tumor list


(GLS - italian project)
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General Information

The malignant, potentially malignant and benign tumours of the skin, which could be called rare (that is, whose incidence is less than 2 per 100.000) are quite numerous. The low incidence of these tumours and the difficulty to collect in only one centre a sufficient number of cases to have enough experience and results, makes difficult both their clinical and histopathological recognition and their prognostic evaluation and treatment.

The main aims of the project are to share cases and create statistics about archives material, to make real time consultation and studies on the natural history of the disease, to prepare qualified personnel, to create guide lines and therapeutic indications: that is, whatever is connected with the consultation of a dynamical file of information and images with whom one could interact in real time from a remote computer. These objectives are strictly linked to those of the WHO Collaborating Centre for Cancer Control of Uncommon Tumours which is situated at the S. Pio X Private Hospital, Milan.

The project will see the sending of clinical information and images and one or more histological sections representative of the observed rare skin tumours to the coordinating centre (server). The histological section will be digitally memorized and the obtained images together with the clinical information and images will be at disposal of the different groups which take part of the project (multi client network). The peripheral centres (clients) will be able to access not only the clinical images but also the histological section and/or different parts of it at different power, simultaneously (asymmetrical system), as if it was seen at the microscope. For the client the program to see the digital images is free of charge and the dimension of this program is quite small, so that it could also be sent via e-mail. The system, which will be used is the ZEM/NIKON one; it has been created for a “multiclient” environment and it includes a server (at the coordinating Centre in Milan “raretumours.org”) and numerous clients connected between them (peripheral centres): in theory up to 65000 clients could be connected simultaneously.

The expected results are the sharing of the cases of rare skin tumours, the creation and the management of a multidisciplinary data base of clinical information and images with the final objective to develop contacts between different Italian and foreign centres in collaboration with the Dermatological and Anatomical Pathology Societies.


For informations contact:

Dr. Claudio Clemente
Anatomia Patologica e Citopatologia
Casa di Cura San Pio X
Via F. Nava 31
20159 Milan, Italy
Tel: +39 (02) 6951-6440
Fax: +39 (02) 6951-6449
e-mail: info@raretumours.org


Tentative list of rare non-melanocytic tumors of the skin

-Tumors of epidermal origin
  Verrucous carcinoma
-Tumors of epidermal appendages
  Tumors of eccrine sweat gland origin
  Porocarcinoma (malignant eccrine poroma)
  Malignant eccrine spiroadenoma
  Malignant nodular hidroadenoma
  Malignant chondroid syringoma
  Mucinous eccrine carcinoma
  Microcystic adnexal carcinoma
  Primary cutaneous adenoid cystic carcinoma
-Tumors of sebaceous gland origin
  Sebaceous carcinoma
-Tumors of apocrine gland origin
  Extramammary Paget’s disease
  Apocrine adenocarcinoma
  Malignant cylindroma
  Maligant hidroadenoma papilliferum
-Tumors of follicular origin
  Trichilemmal carcinoma
  Malignant proliferating trichilemmal tumor
  Pilomatrix carcinoma
-Tumors of fibrous tissue origin
  Dermatofibrosarcoma protuberans
  Atypical fibroxanthoma
  Malignant fibrous histiocytoma
  Angiomatoid fibrous histiocytoma
  Epithelioid sarcoma
  Synovial sarcoma
-Tumors of muscle origin
-Malignant rhabdoid tumor
-Tumors of adipose origin
-Tumors of vascular origin
  Epithelioid hemangioedothelioma
  Malignant endovascular papillary angioendothelioma
  Retiforma hemangioendothelioma
  Hemangiopericitoma (?)
-Merkel cell carcinoma
-Tumors of neural origin
-Malignant granular cell tumor
-Intravascular lymphomatosis (malignant angioendotheliomatosis)
-Maligant histiocitosis
-Extramedullary plasmocitoma